The game between Wake Forest and Notre Dame scheduled for Sept. 26 has been postponed after seven of the Fighting Irish's 94 tests on Monday returned a positive result for COVID-19, the school announced.
Notre Dame has paused all football-related activities until further testing is completed. Including those who tested positive last week, 13 student-athletes from the school are currently isolated, with 10 in quarantine.
"With student-athlete health and safety our primary focus, we will continue to follow our prevention protocols and ongoing testing procedures," head coach Brian Kelly said in a statement. "We managed an increase in positivity rates in August, and the players handled it wonderfully.
"We knew COVID would present challenges throughout the season, and we'll always put student-athlete health and safety at the forefront of our decision making. We look forward to resuming team activities and getting back on the playing field."
The ACC announced Wednesday that the game is now scheduled to take place on Dec. 12. The conference also moved Wake Forest's matchup against Campbell from Oct. 9 to Oct. 2.
Sixteen games have now been postponed this season due to COVID-19 concerns, according to Nick Bromberg of Yahoo Sports.
Notre Dame, an independent program, temporarily joined the ACC this year as a result of a pandemic-adjusted football schedule.