The three won't see the ice for precautionary reasons, according to TSN's Darren Dreger.
Each player will become an unrestricted free agent on July 1 and has been rumored to be on the move ahead of the Feb. 25 trade deadline.
Stone, Duchene, and Dzingel rank first, second, and third, respectively, among forwards in team scoring.
Despite a tumultuous campaign for Ottawa, Dzingel has already set a career high in points with 44, and both Stone and Duchene are on pace to best their previous highs for points in a season.
After their tilt with the Devils, the Senators head home to play the Columbus Blue Jackets Friday and the Calgary Flames Sunday ahead of Monday's trade deadline.