49ers' Samuel to miss at least 2 games; McCaffrey questionable for MNF

San Francisco 49ers wide receiver Deebo Samuel will miss at least the next two games with a hairline fracture in his shoulder, head coach Kyle Shanahan said Saturday, according to ESPN's Adam Schefter.

Meanwhile, running back Christian McCaffrey is questionable to play Monday night against the Minnesota Vikings due to an oblique injury, the team announced.

Left tackle Trent Williams is also doubtful with an ankle injury.

Samuel will miss contests against the Vikings and Cincinnati Bengals before the 49ers enter a bye week. The earliest he could return is Week 10 against the Jacksonville Jaguars.

McCaffrey missed practice Thursday and Friday before participating in a limited capacity Saturday.

The star running back said multiple times after Saturday's practice that he feels "great", according to NBC Sports' Matt Maiocco.

Behind McCaffrey on the depth chart are Elijah Mitchell and Jordan Mason. Jaylon Moore is expected to be Williams' backup at left tackle after he played two snaps in relief of the Pro Bowler last week.

Samuel, McCaffrey, and Williams were all injured in the Week 6 loss to the Cleveland Browns, the 49ers' first defeat of the season.