"Nobody's to blame. We're in a pandemic," said Vrabel, according to NFL Network's Aditi Kinkhabwala. "Unfortunately, things happen."
The Titans will play the Steelers on either Monday or Tuesday after four players and five personnel members tested positive for COVID-19.
"Some of them are indeed experiencing flu-like symptoms, (but) nothing out of the ordinary," said Vrabel, per Kinkhabwala. "We anticipate they will feel better shortly."
Vrabel confirmed he wasn't among the five personnel who tested positive.
Defensive tackle DaQuan Jones, long snapper Beau Brinkley, and practice squad tight end Tommy Hudson were all placed on the reserve/COVID-19 list Tuesday. A fourth player who's yet to be named reportedly tested positive in the latest round of testing.
The Minnesota Vikings - the Titans' Week 3 opponents - haven't recorded a positive test.