Arizona Cardinals quarterback Kyler Murray was replaced by Brett Hundley in the second half of Sunday's game versus the Seattle Seahawks after suffering a hamstring injury.
Murray was labeled questionable to return, but never did. He appeared hurt while coming to the bench at the end of a third-down scramble.
The rookie signal-caller helped the Cardinals get out to a double-digit lead over the Seahawks, throwing one touchdown pass and totaling 158 yards of offense before leaving. Even with Murray sidelined, Arizona earned a surprising 27-13 victory in Seattle.
Murray, the first overall pick in 2019 out of Oklahoma, entered Week 16 with 21 touchdowns (17 passing, four rushing) and 10 interceptions.