"He's available," Giants coach Pat Shurmur told reporters, according to SNY's Ralph Vacchiano. "We'll see if he's back. If he is, he'll be ready to go. I just choose not to tell you right now."
Barkley missed three games after spraining his ankle on Sept. 22. Initial reports suggested the second-year star could be sidelined for as many as eight weeks.
Despite the injury, Barkley still leads the Giants in rushing with 237 yards and a touchdown over three appearances. New York went 1-2 while he was out.
Along with Barkley, tight end Evan Engram practiced fully Friday and is expected to return following a one-game absence due to a sprained MCL. Engram leads the team in receiving with 373 yards and two touchdowns.