The Premier League leader overcame Napoli 4-2 in an enthralling bout, marking a huge statement against a side also lauded for breathless attacking football. After four matches in Group F, City has a full complement of points.
The host opened the scoring after 21 minutes thanks to some superb interplay between Lorenzo Insigne and Dries Mertens. The latter returned the ball to his Italian teammate with a stunning pass spun perfectly into his path, and Insigne's finish was beautifully lifted over Ederson Moraes.
Headers from Nicolas Otamendi and John Stones either side of half-time put City ahead, but the clash was levelled when Jorginho converted from 12 yards. The penalty was awarded after a clumsy challenge from Leroy Sane tumbled Raul Albiol in the area.
Then, in a ferocious counter-attack spearheaded by Sane, Aguero enjoyed breaking a scoring record that had stood since Eric Brook called time on his career in 1939:
Manchester City now looks to complete the job in Group F. Guardiola's lot currently holds a three-point cushion over second-placed Shakhtar Donetsk, and faces the Ukrainian giant in the final matchday on Dec. 6.