Bryan Abreu, Luis Garcia, Ronel Blanco, Cristian Javier, Pedro Baez, Enoli Paredes, Francis Martes, and Hector Velazquez are at home, Baker added.
Astros general manager James Click wouldn't reveal whether any players had tested positive.
"Part of the reason that so many players are away from camp for health and safety (protocols) is because we want to cast a wide net," Click said. "And the protocols cast a wide net to make sure if there are delays between contagious stages and positive test results, that those don't lead to an outbreak.
"We are following Major League Baseball's health and safety protocols and this is what they call for. We and the league believe that, by following them, we will ensure the rest of the guys are not exposed and we can continue to get ready for the season."