Mitchell went bogey-free around a tough Quail Hollow Club to secure the 54-hole lead. He gained over three strokes off the tee in Round 3 to lead the field in driving and gained roughly 1.5 on the greens.
The 29-year-old Tennessee native will look to hang on for a second career PGA TOUR title. He claimed his first at the Honda Classic in 2019.
However, Mitchell will need to fend off a pair of major champions in hot pursuit if he's going to return to the winner's circle.
McIlroy, who will play in Sunday's final pairing, shot 68 despite a costly double-bogey on No. 12. At one point, the Northern Irishman held a two-shot advantage.
Woodland, meanwhile, co-led after 36-holes but dropped into a tie for second with his 1-under 70.
Here's how the top of the leaderboard stands with 18 holes remaining:
|Place||Player||To Par||R3 Score|