Helm caught Lindholm from behind just over five minutes into the third period.
The Red Wings center was assessed a five-minute slashing major and game misconduct, while the Flames winger was simultaneously handed an interference minor, as he hit Helm up high beforehand.
Lindholm, who scored his fifth goal of the season in the second period, left the game and didn't return. Helm potted his third marker of the campaign less than 30 seconds after Lindholm's goal.
Flames head coach Bill Peters had no update on Lindholm's condition postgame, according to Postmedia's Wes Gilbertson.
The Flames defeated the Red Wings 5-1.