The New Orleans Saints will be missing their top two running backs for the Thanksgiving game against the Buffalo Bills.
Mark Ingram is inactive for Thursday's matchup due to a knee injury, according to Nick Underhill of NewOrleans.Football.
Alvin Kamara has already been ruled out for a third straight game due to a knee injury, meaning Tony Jones Jr. will likely get the start.
Jones has rushed for 79 yards on 22 carries in a backup role this season.
New Orleans will also be without All-Pro right tackle Ryan Ramczyk and defensive end Marcus Davenport.
