The Miami Dolphins' wide receiver corps took another hit Wednesday.
Hurns announced his decision not to play Tuesday.
Hurns and Wilson finished fourth and fifth, respectively, in receiving yards for the Dolphins last season behind breakout star DeVante Parker, tight end Mike Gesicki, and sophomore wideout Preston Williams.
Losing two of their more experienced wideouts is a major blow to the Dolphins.
The AFC East club is likely intent on starting rookie quarterback Tua Tagovailoa despite the limited offseason work and training camps, but the team could be forced to ask the former Alabama standout to take over an even more talent-poor offense than expected.
Wilson caught 43 passes for 351 yards and one touchdown last season and took a pay cut this offseason to remain with the Dolphins.