Cooks will miss his second straight game as he recovers from a concussion, while Havenstein could be out for multiple weeks with a meniscus injury.
Additionally, starting center Brian Allen will miss the remainder of the season with an MCL injury, McVay said.
Cooks visited a specialist in Pittsburgh after suffering his second concussion of October. The 26-year-old suffered three known concussions prior to this campaign.
McVay's offense struggled in a Week 10 loss to the Pittsburgh Steelers due in large part to inconsistencies along the offensive line.