Aurelien Tchouameni dropped out of Real Madrid's squad to face Las Palmas in La Liga on Sunday "due to discomfort in his left leg", said the Spanish champions in a statement.
The French midfielder, often used in defence by Madrid, was replaced in the squad by Jacobo Ramon and Chema Andres for the home match that kicks off at 1515 GMT.
Los Blancos are a point behind La Liga leaders Atletico Madrid, who lost 1-0 on Saturday at Leganes. Real host RB Salzburg in a crucial Champions League game on Wednesday.
