Barkley frustrated with persistent injury woes: 'It doesn't make sense'

With Saquon Barkley once again facing time on the sidelines after suffering a low ankle sprain in Week 5, the New York Giants running back's injury woes are starting to wear on him.

"I'll be honest, it's frustrating. It doesn't make sense why it's happening," Barkley said Thursday, according to Ralph Vacchiano of SNY.

He added: "But I can't keep that mindset. You can't get anywhere with it. Everything happens for a reason."

Barkley is reportedly expected to be out for at least a week. It'll be the third straight campaign the 24-year-old has missed games.

He played in all 16 contests in his debut season in 2018, rushing for 1,307 yards and 11 touchdowns to earn Offensive Rookie of the Year honors. However, Barkley sat out three games in 2019 due to an ankle injury before suffering a torn ACL in Week 2 last season.

"Being mad at myself, that's the only thing I could be," said Barkley. "Mad at myself, mad at the world, mad at everybody."

Prior to his latest injury, Barkley appeared to be struggling to shake off the rust and return to his Pro Bowl form.

The running back was averaging just 3.6 yards per carry through five games and was second on the team in rushing yards with 195 behind quarterback Daniel Jones.

Barkley isn't the only Giants player ailing ahead of Week 6. Jones suffered a concussion and wide receiver Kenny Golladay hyperextended his knee against the Dallas Cowboys. Both are in doubt for Sunday's game against the Los Angeles Rams.