Frederick announced in August that he was diagnosed with a rare autoimmune disorder called Guillain-Barre Syndrome. He wasn't given a timetable for a return to the field and hasn't played this season.
Frederick told DallasCowboys.com in early September that he was still experiencing numbness in his feet and hands.
The Cowboys were holding off from making the move, but now the team has gained more clarity on Frederick's circumstances.
"We are in better shape today to make a decision about IR for a few weeks than we were when we first learned of this," owner Jerry Jones said to David Helman of DallasCowboys.com.
Without the four-time Pro Bowler and 2016 All-Pro, the Cowboys have gone with Joe Looney at center.
Despite Frederick's absence, Cowboys running back Ezekiel Elliott leads the league with 426 rushing yards.
Dallas also placed wide receiver Terrance Williams on IR.