Phoenix, AZ (Sports Network) - Paul Konerko homered for the third straight day as Chicago beat Arizona, 8-2, in the rubber match of a three-game interleague series.
Philip Humber (7-3) lasted 7 2/3 innings, allowing two runs on seven hits and a walk to earn his fourth straight win.
"If you look at his stuff, it's not luck," Konerko said of Humber. "He's got a good arm, he's got all the pitches and he's got the location. I think he's on his way."
Alex Rios also went deep for the White Sox, who won two in a row after dropping their previous three.
Josh Collmenter (4-3) allowed three runs on five hits and a walk while striking out five in defeat.
Justin Upton was 3-for-4 and knocked in a run, but Arizona lost for the fourth time in six games.
Collmenter retired the first nine batters he faced before Juan Pierre led off the fourth with a single. Omar Vizquel followed with a single into center field that moved Pierre to third and Alexei Ramirez then hit an RBI groundout to give Chicago a one-run advantage.
The White Sox added to their lead in the seventh inning when Konerko hammered an 0-1 fastball into the left-field bleachers and two batters later, Rios pulled an 0-2 fastball into almost the same spot.
"I felt good," Collmenter said. "Everything felt good, I had good command and I was back to my normal stuff, and other than the seventh inning, everything went well."
Chicago put the game out of reach in the eighth. Ramirez added his second run- scoring groundout of the night to go along with a Brent Lillibridge RBI single and a three-run double by A.J. Pierzynski to make it an 8-0 game.
Arizona put a couple runs on the board in the eighth when Ryan Roberts doubled in Gerardo Parra and later crossed the plate on an Upton base-hit, but it was too little, too late.
The D-Backs later loaded the bases with two outs in the inning, but pinch- hitter Kelly Johnson hit a weak grounder to second base for the easy force out to end the inning.
Trailing 1-0 in the fifth, Arizona had a chance to take control of the game but would fail to push a run across the plate. With men on first and second and two down, Humber threw a wild pitch to move both runners into scoring position. But he was able to get himself out of the jam by fanning Roberts on a 3-2 slider to end the inning.