Farley will spend the year training for the NFL.
"I am opting out due to uncertain health conditions and regulations, and all the other opts-outs going on in football right now," Farley said in a video statement alongside his family. "I tragically lost my mother, Robin, Jan. 2, 2018, to an illness, and I cannot afford to lose another parent or loved one."
Farley's mother died from breast cancer.
The Hokies standout racked up four interceptions last season, entering the conversation for the best cornerback prospect in the 2021 NFL Draft.