In April 2018, City's bus came under attack ahead of their Champions League quarterfinal clash with Liverpool when fans threw bottles, cans, and other objects, causing extensive damage.
Despite the presence of a police escort, Guardiola claims authorities didn't do enough to prevent the attack.
"No, hopefully it won’t happen again," he said on Friday, according to the Manchester Evening News. "The police knew it for the Champions League game and didn’t do anything. Hopefully it will be an incredible game and the same that happened two seasons ago won’t happen."
It appears local authorities are better prepared this time, as the Merseyside Police claim to have been alerted to a social media post urging Liverpool fans to line the streets and bring "pryo, pints (and) flags".
"We are aware of one poster on social media regarding a bus welcome," said Merseyside Police superintendent Paul White, according to BBC Sport. "The corresponding last fixture ran smoothly and we are working to ensure this game can be enjoyed safely by all as well as minimizing any disruption to local residents and roads."
Liverpool issued an apology after last season's incident, with manager Jurgen Klopp blaming "idiots" for ruining an otherwise festive atmosphere.
On Friday, Klopp also warned that Liverpool supporters shouldn't overstep the line when City comes to town.
"If someone from Man City is concerned still, it's our fault," Klopp said, according to Rob Dawson and Melissa Reddy from ESPN FC.
"We all didn't throw a bottle, but it was one of us," Klopp added. "All of us have to make sure that something like that never happens again. We will do everything to make sure it doesn't happen again."