Report: Cardinals' Iupati, Mathis could have fractured ankles

Arizona Cardinals starting guards Mike Iupati and Evan Mathis may both have fractured their ankles during Thursday's win over the San Francisco 49ers, Mike Jurecki of FOX Sports 910 reports.

Both players left the game and will undergo MRIs to determine the extent of their injuries

Despite losing both guards, Cardinals running back David Johnson rushed for a season-high 157 yards and two touchdowns.