The star junior cautiously walked into the tunnel with Sooners trainers under his own power after exiting the contest.
"We'll see on Rodney," head coach Lincoln Riley said postgame, according to ESPN's Jake Trotter. "Don't have anything definitive. We'll hope for the best."
Anderson rushed for 19 yards and a touchdown on six carries against the Bruins before the injury. He posted 1,161 yards with 13 scores on the ground in 2017.