NFL Betting Preview: Week 15 picks

Each week during the NFL season, theScore will handicap each of the week's matchups and offer up a three-pack of picks.

Arizona Cardinals (-3) at Philadelphia Eagles

The Eagles appeared ready to give up on their season before back-to-back victories put the team back in contention for a division title. The Cardinals will make a long trip out to Philadelphia for this one, but they'll have had 10 days to prepare. Arizona is built to attack the Eagles where they're weakest, and that's in the secondary. Carson Palmer's going to light them up. Cardinals 41, Eagles 24

Washington Redskins (+1) vs. Buffalo Bills

The schedule-makers really didn't do the Bills any favors here. Not only are they playing their second consecutive road game, but they'll be playing seven games in seven different cities, and not long before that, they were in London. That's a lot of travel. The Redskins are playing to win a division, and they've been better at home. Redskins 24, Bills 13

New Orleans Saints (-3) vs. Detroit Lions

It's been a disappointing season for both sides. But the Lions seemed to have folded up shop following a heartbreaking loss to the Packers, while the Saints showed a desire to play for the win last week against the Buccaneers. With remaining games against the Lions, Jaguars, and Falcons, at some point Sean Payton or Drew Brees stood in front of this group and challenged them to win out. Saints 37, Lions 21

Remaining Week 15 matchups

Tampa Bay Buccaneers (+1.5) at St. Louis Rams

The Buccaneers can stop the run, and it's difficult to imagine the Rams generating offense any other way. Buccaneers 24, Rams 10

New York Jets (-3) at Dallas Cowboys

It's simple: The Jets have a quarterback, and the Cowboys don't. Jets 20, Cowboys 14

Chicago Bears (+5.5) at Minnesota Vikings

The Bears started the season 0-3, with losses by an average margin of 19.7 points. Since then, they're 5-5 with losses by an average margin of 3.4 points. In that time, they're 4-1 on the road. Bears 26, Vikings 20

Jacksonville Jaguars (-3) vs. Atlanta Falcons

The Falcons have gone 0-6 since a 6-1 start, while the Jaguars are 3-1 in their last four home games. Jaguars 23, Falcons 17

Houston Texans (OFF) at Indianapolis Colts

Both teams are a mess right now. The only trustworthy unit in this matchup is the Texans' defense. Texans 13, Colts 10

New York Giants (+5) vs. Carolina Panthers

The Panthers are one of the few teams with a cornerback that can match up with Odell Beckham Jr., but they're not built to handle additional injuries on offense. Giants 24, Panthers 23

Tennessee Titans (+14) at New England Patriots

The Titans lost to the Jets by a 22-point margin, but they've been more competitive than that in recent weeks. Patriots 31, Titans 21

Kansas City Chiefs (-7) at Baltimore Ravens

The Chiefs are rolling along with seven wins in a row by an average margin of 17.0 points. The Ravens will start Matt Schaub at quarterback. Chiefs 29, Ravens 10

Cleveland Browns (+14.5) at Seattle Seahawks

The Browns are bad at stopping the run, but the Seahawks don't have a running back. Time for Russell Wilson to come back to Earth. Seahawks 20, Browns 14

Green Bay Packers (-3) at Oakland Raiders

Eddie Lacy's running well. Mike McCarthy's calling plays again. Things are good in Green Bay. Packers 28, Raiders 20

Pittsburgh Steelers (-6.5) vs. Denver Broncos

The Broncos' defense has excelled this season, but the team's enjoyed a favorable schedule. Ben Roethlisberger and the Steelers' offense is a step up in class. Steelers 26, Broncos 17

Miami Dolphins (+2) at San Diego Chargers

The Dolphins are a mess right now, but the Chargers are an even bigger mess. Dolphins 28, Chargers 27

San Francisco 49ers (+5) vs. Cincinnati Bengals

The 49ers are playing much better football at home, and it's too early to justify investing in AJ McCarron. 49ers 19, Bengals 17

(Lines courtesy: BetCRIS.com)