Captain Pogba hobbles off with suspected hamstring issue
Pogba stretched for a tackle, and then staggered around the pitch until surrendering to the ailment and calling for his substitution. He was replaced by Marouane Fellaini in the Champions League tilt.
The Frenchman suffered two similar issues in March and May, Simon Stone of BBC Sport reports, missing four club outings.
"I haven't spoken with the medical department. This is why we have a squad, we won't cry about injuries," Jose Mourinho told MARCA's Chris Winterburn post-match, before disclosing that Pogba will probably miss Sunday's Premier League hosting of Everton.
Pogba, 24, was given the captain's armband ahead of kick-off despite Chris Smalling, who has held the distinction in the past, also starting at Old Trafford. Ashley Young took over skipper duties when Pogba was withdrawn.