Isner tops Raonic to reach 1st major semifinal
Matthew Stockman / Getty Images Sport / Getty

John Isner has reached his first Grand Slam semifinal on his 41st appearance.

The hard-serving American beat Milos Raonic of Canada 6-7 (5), 7-6 (7), 6-4, 6-3 to set up a meeting with Kevin Anderson of South Africa in Wimbledon's last four.

Isner's 41 attempts to make a semifinal at a major is the second most in the 50-year professional era, behind Sam Querrey, who made the last four at Wimbledon last year with his 42nd try.

Isner has yet to be broken at this year's tournament and saved the only break point he faced on Wednesday. Raonic hit 31 aces to Isner's 25 but was broken three times, including the last game of the match.

Isner tops Raonic to reach 1st major semifinal
  Got something to say? Leave a comment below!
.@stanwawrinka shook off a tough test from @karenkhachanov t...
Highlights in Wawrinka's win against Khachanov
Laver Cup diary: McEnroe urges 'home' support | Tennismash
Federer Is Bringing Up Baby
Chair Umpire Who Counseled Kyrgios Is Suspended by ATP Tour
Finalist in 2016, how far can #StanTheMan go this year? Hig...
Highlights in Wawrinka's win over Bedene
All aboard the 🎾 skills school with @ThiemDomi 😯🛥️
All about that hand-eye coordination
A winning start to the St. Petersburg Open for Martin Klizan...
Highlights in Klizan's win over Donskoy