NFL Game Summary - Indianapolis at San Francisco

San Francisco, CA (Sports Network) - Andrew Luck's return to the Bay Area was a smashing success, much to the chagrin of his college coach.

The ex-Stanford star ran for a touchdown while putting together an efficient effort under center, and the Indianapolis Colts clamped down on the defensive end on their way to an impressive 27-7 victory over the defending NFC champion San Francisco 49ers at Candlestick Park.

Luck completed 18-of-27 passes for 164 yards and did turn the ball over in outplaying young counterpart Colin Kaepernick, while getting a big assist from a Colts defense that held the struggling 49ers to 254 total yards and held Kaepernick firmly under wraps.

Indianapolis (2-1) also churned out 179 rushing yards, with Ahmad Bradshaw gaining 95 and a touchdown on 19 carries and the newly acquired Trent Richardson scoring on his first touch as a Colt.

One week after committing four turnovers in a 29-3 loss at Seattle, Kaepernick managed just 150 yards on 13-of-27 passing while being intercepted once and losing a fumble.

Frank Gore finished with 82 rushing yards on 11 attempts for San Francisco (1-2), which fell under .500 for the first time in the three-year tenure of Jim Harbaugh, Luck's former mentor at Stanford.