Milan - Under-pressure Frank de Boer saw his Inter side hold on with 10 men to beat Premier League outfit Southampton 1-0 in its Europa League clash at San Siro on Thursday.
Antonio Candreva got the only goal of the game midway through the second half for the Serie A club, which was forced to play out the final 13 minutes a man down after Marcelo Brozovic was sent off.
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It was a cruel result for Southampton, which had been the better side and saw Jay Rodriguez have a goal disallowed early in the second half.
The result sees the Saints remain on four points in Group K, two points behind Sparta Prague, which beat Hapoel Be'er Sheva 1-0 in Israel.
For Inter, it was a first three points in the competition, and the win against a team in good form in the Premier League should buy Dutch coach De Boer some time as the Nerazzurri struggle for results.