San Francisco 49ers left tackle Joe Staley missed his second consecutive practice with a knee injury.
Staley was riding a stationary bike, according to Cam Inman of the Bay Area News Group.
The 49ers' left tackle played in the team's first four games and it's unclear when he suffered the injury.
If Staley can't play Sunday against the New York Giants, expect Trenton Brown to take his place in the starting lineup.