San Francisco 49ers defensive end Dee Ford is listed as out for Sunday's matchup with the New York Jets due to a neck injury.
Ford didn't practice all week and was previously considered questionable for Week 2.
The pass-rusher had surgery during the offseason to clean up a chronic knee issue but played 56% of San Francisco's Week 1 defensive snaps.
Ford joins a growing list of 49ers players who are expected to miss time. The team placed wide receiver Deebo Samuel and cornerback Richard Sherman on short-term injured reserve earlier this week, and star tight end George Kittle will also miss Sunday's tilt with a knee sprain.
Nick Bosa and Arik Armstead will receive most of the work on the edge in Ford's absence, with Kerry Hyder and Kentavius Street spelling them.