The Arizona Cardinals will be missing more than just David Johnson when they take on the Indianapolis Colts on Sunday.
The Cardinals will also be without four other offensive starters, as tight end Jermaine Gresham, receiver John Brown, as well as offensive linemen Mike Iupati and D.J. Humphries are sidelined with injuries. That's bad news for a unit that struggled to move the ball in a Week 1 loss to the Detroit Lions.
Kerwynn Williams will get the start at running back, while Ifeanyi Momah slots in at tight end. Alex Boone and John Wetzel will fill in on the offensive line.