Vanderbilt fired head coach Derek Mason, the school announced Sunday.
Offensive coordinator Todd Fitch will take over on an interim basis.
"On behalf of the entire Vanderbilt community, I want to extend my deepest gratitude to coach Mason for his many years of dedication and service leading our football program," athletic director Candice Storey Lee said in a statement. "Derek cares deeply about the student-athletes under his charge. His tenure at Vanderbilt will be remembered for his steadfast commitment to our student-athletes, not only on the field, but in the classroom and as young people."
Mason spent seven seasons with the Commodores, reaching two bowl games. The 51-year-old never finished a season with a winning record and lost all eight games this year.
Mason arrived in Nashville in 2014 as the replacement for James Franklin, who left for Penn State after posting 24-15 mark across three seasons. He leaves the program with a cumulative record of 27-55.
The Commodores are the only winless team in the SEC. They join South Carolina as schools from their conference with a vacancy at head coach.