Paris - Holders Paris Saint-Germain were drawn at home against either second-tier Grenoble or Ligue 1 Strasbourg in the last 32 of the French Cup on Monday.
The tie between Grenoble and Strasbourg will take place on January 16 after it was originally postponed due to a frozen pitch at Grenoble's Alpine stadium.
The Parisians have won their last 43 domestic cup matches, a record stretching back to February 2014.
Thierry Henry's Monaco face a lengthy trip north to play Metz near the German border while Lyon travel to Amiens in one of four potential top-flight clashes.
Last year's runners up Les Herbiers head to Villefranche from a league above them.
The lowest teams left in the competition in sixth tier Viry-Chatillon and Noisy-le-Grand will to face Ligue 1 Caen and Bastia from the fifth level of French football.
French Cup last 32 to be played on Jan. 22-23:
Sete v Lille or Sochaux
Monaco v Metz
Amiens v Lyon
Saint-Etienne v Dijon
Toulouse v Reims
Nancy v Guingamp
SC Bastia v Noisy-le-Grand
Saint-Pryve Saint-Hilaire v Rennes
Andrezieux v Lyon Duchere
Bergerac v Orleans
Vitre v Le Havre
Viry-Chatillon v Caen
Paris-SG v Grenoble or Strasbourg
Sannois Saint-Gratien v Nantes
Villefranche Beaujolais v Les Herbiers
Marignane Gignac v Croix