Premier League Matchday 22 odds and betting preview

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A stoppage-time winner meant we took a small hit on our most recent slate of picks to drop our net profit this season to $1,165.

Let's get back to our winning ways this weekend.

Arsenal (-125) at Crystal Palace (+310), Draw (+290)

Arsenal have experienced mixed results under new manager Mikel Arteta, with one win, one draw, and one loss in the league. Coming off a pair of home victories over Manchester United and Leeds United, the Gunners will ride a wave of momentum into a match that presents a different challenge.

You know what you're getting when you visit Selhurst Park. Arsenal will have to really earn the three points here, as Crystal Palace will dig in and leave everything on the pitch. Are the Gunners willing to do the same? I think they'll have to settle for a point in what is usually one of the more fascinating London derbies.

Pick: Draw (+290)

Brighton (+300) at Everton (-110), Draw (+270)

Expect a major response from Everton on Saturday after they were dumped out of the FA Cup by rivals Liverpool last weekend. The Toffees were toothless and bereft of creativity in the second half after Adrian produced some terrific saves in the opening 45 minutes to deny them the lead. Everton's league form has been drastically improved under Carlo Ancelotti and they should be full of energy for this one at Goodison Park.

Brighton put together a strong first half of the campaign, but if there's one knock against Graham Potter in his inaugural season as Seagulls boss, it's that their away form needs to improve. It's unlikely we see it here, though, with trips in the coming weeks to West Ham and Bournemouth serving as much likelier targets.

Pick: Everton (-110)

Liverpool (-150) at Tottenham (+350), Draw (+333)

You've read enough in this column - as well every other article - to know by now how great Liverpool have been. There's very little doubt the Reds are set to end their title drought, to the point that even the most superstitious of supporters aren't especially bothered by that statement.

Their unbeaten run will be put to the test in north London on Saturday, but how difficult will it really be? Without Harry Kane, it's hard to see how Tottenham trouble Liverpool at the back. I typically hate laying juice in soccer, but this is a spot in which there's still value in the line, as it doesn't appropriately represent the true gulf in quality between the two sides. Spurs are in dire form and there's little about their play of late that inspires belief in their ability to get anything from this match.

Pick: Liverpool (-150)

Watford (+170) at Bournemouth (+160), Draw (+230)

It's been a miserable two months for Bournemouth, with Eddie Howe going from one of England's most coveted young managers to in danger of losing his job. There's still far too much talent in this Cherries side for it to be faced with relegation, but Bournemouth have to play themselves out of this miserable run of form. While injuries haven't helped matters, there's no excuse for the squad falling as far as it has.

Watford are just a point behind Bournemouth with both situated in the bottom three. However, recent form favors the Hornets, who have taken 10 points from their last 12. Still, they've won just once from 10 away matches in the league this season and will gladly accept a point here to continue their unbeaten run. Bournemouth could also desperately use even a single point right now.

Pick: Draw (+230)

Alex Moretto is a sports betting writer for theScore. A journalism graduate from Guelph-Humber University, he has worked in sports media for over a decade. He will bet on anything from the Super Bowl to amateur soccer, is too impatient for futures, and will never trust a kicker. Find him on Twitter @alexjmoretto.