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NFL Week 16 Opening Line Report: Jaguars in unfamiliar position

Tommy Gilligan / USA TODAY Sports

The Week 15 card was littered with unders, which is more often than not a great sign for the books. Bettors will look to take back some of that cash in Week 16, with a slate of games that features a pair of Saturday matchups.

The Jacksonville Jaguars are installed as favorites for the first time in 42 consecutive games for Thursday night's matchup against the Tennessee Titans.

The Saturday slate sees the Philadelphia Eagles visit the Washington Redskins as eight-point favorites, and the San Francisco 49ers giving away 2.5 points to the San Diego Chargers.

The Green Bay Packers struggled in a trip to Buffalo on Sunday, but they're back as double-digit favorites in a matchup with the Tampa Bay Buccaneers.

Even with the uncertainty surrounding quarterback Cam Newton, the Carolina Panthers open as 3.5-point favorites against the Cleveland Browns.

Here's a peek at all of the opening lines for Week 16 of the NFL season.

More NFL Betting Resources

Week 16 Staff Picks (Wednesday)
TNF Preview (Thursday)
Week 16 Betting Preview (Friday)
Game Day Betting Update (Sunday)
MNF Preview (Monday)

Thursday, December 18

Tennessee Titans at Jacksonville Jaguars (-3), total: 40.5

Saturday, December 20

Philadelphia Eagles (-8) at Washington Redskins, total: 50.5

San Diego Chargers at San Francisco 49ers (-2.5), total: 42.5

Sunday, December 21

Minnesota Vikings at Miami Dolphins (-7), total: 43

Green Bay Packers (-10.5) at Tampa Bay Buccaneers, total: 47

Detroit Lions (-4) at Chicago Bears, total: OFF

Atlanta Falcons at New Orleans Saints (-6.5), total: OFF

New England Patriots (-10) at New York Jets, total: 47

Kansas City Chiefs at Pittsburgh Steelers (-3.5), total: 45.5

Cleveland Browns at Carolina Panthers (-3.5), total: OFF

Baltimore Ravens (-3.5) at Houston Texans, total: 42

New York Giants at St. Louis Rams (-4.5), total: 44

Buffalo Bills (-5.5) at Oakland Raiders, total: 38.5

Indianapolis Colts at Dallas Cowboys (-3), total: 55.5

Seattle Seahawks (-7.5) at Arizona Cardinals, total: 43

Monday, December 22

Denver Broncos (-3.5) at Cincinnati Bengals, total: 48.5

- Lines courtesy Scoresandodds.comBetOnline

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