NFL Game Summary - Houston at San Francisco

San Francisco, CA (SportsNetwork.com) - Houston, we have a problem.

Matt Schaub became the first quarterback since the AFL-NFL merger to throw a pick-six in four straight games, as the Texans suffered a 34-3 loss to the San Francisco 49ers on Sunday night.

Schaub became the topic of debate in Houston following last week's overtime loss to the Seattle Seahawks. With 2:40 left in regulation, Richard Sherman picked off Schaub and raced 58 yards the other way to tie the game at 20.

On Sunday, Schaub completed just 19-of-35 passes for 173 yards and three interceptions. Schaub has thrown six picks during Houston's three-game losing streak.

T.J. Yates took over in the fourth quarter and connected on 3-of-5 passes for 15 yards for the Texans (2-3).

San Francisco cornerback Tramaine Brock had two interceptions and returned one for a touchdown. Defensive tackle Tony Jerod-Eddie had the other interception.

Colin Kaepernick completed 6-of-15 passes for 113 yards and a touchdown for the 49ers (3-2), who have won two in a row.

Frank Gore carried the ball 17 times for 81 yards and a score, while Vernon Davis caught three passes for 88 yards and a touchdown.