Schedule
Pittsburgh
| Date | Opponent | Score/Time | Stadium |
|---|---|---|---|
| Sep. 03 | vs. Buffalo | W 35 - 16 | Heinz Field |
| Sep. 10 | vs. Maine | W 35 - 29 | Heinz Field |
| Sep. 17 | at Iowa | L 27 - 31 | Kinnick Stadium |
| Sep. 24 | vs. Notre Dame | L 12 - 15 | Heinz Field |
| Sep. 29 | vs. South Florida | W 44 - 17 | Heinz Field |
| Oct. 08 | at Rutgers | L 10 - 34 | High Point Solutions Stadium |
| Oct. 15 | vs. Utah | L 14 - 26 | Heinz Field |
| Oct. 26 | vs. Connecticut | W 35 - 20 | Heinz Field |
| Nov. 05 | vs. Cincinnati | L 23 - 26 | Heinz Field |
| Nov. 12 | at Louisville | W 21 - 14 | Papa John's Cardinal Stadium |
| Nov. 25 | at West Virginia | L 20 - 21 | Mountaineer Field |
| Dec. 03 | vs. Syracuse | W 33 - 20 | Heinz Field |
| Jan. 07 | vs. Southern Methodist | L 6 - 28 | Legion Field |
