Baltimore Orioles (5-5) at Boston Red Sox (7-3), 4:05 p.m. (ET)

(SportsNetwork.com) - Both Clay Buchholz and Chris Tillman followed up season- opening gems with some mighty struggles in their last trip to the mound.

The right-handers both look to rebound on Saturday night when the Boston Red Sox and Baltimore Orioles square off in the second contest of a four-game series.

Both Buchholz and Tillman picked up victories on April 6, with Buchholz shutting down Philadelphia with seven scoreless innings of three-hit ball in the Red Sox's victory over the Phillies. Tillman, meanwhile, scattered a run over 6 2/3 innings to help the Orioles top the Tampa Bay Rays.

Buchholz followed up with a terrible outing versus the New York Yankees on Sunday. The 30-year-old made his second straight outing on the road and was drilled for 10 runs -- nine earned -- on nine hits and two walks over 3 1/3 innings. He was taken deep twice during a seven-run first inning.

The Boston hurler came out of the loss with a 7.84 earned run average on the season.

"I'm not going to let one start affect the way I feel about the year that we're going to have or how I feel," said Buchholz.

Tillman, meanwhile, was roughed up by the Toronto Blue Jays on Sunday in a 10-7 loss, charged with seven runs on seven hits and three walks in 2 2/3 innings. The 27-year-old served up a two-run homer in the first inning, a solo shot in the second and then yielded another four runs in the third.

Tillman saw his ERA jump to 7.71.

Buchholz is 9-4 with a 3.86 ERA versus the Orioles, while Tillman has posted a solid 7-3 mark and 2.69 ERA against the Red Sox.

The Red Sox won for the third time in four games by taking last night's opener, 3-2, on Xander Bogaerts' run-scoring single in the bottom of the ninth that chased home Mike Napoli from second base.

"When you're going bad, you don't get anything like that to happen," said Bogaerts, who raised his average to .382.

Ryan Hanigan slugged a two-run homer for the Red Sox, who are off to a 7-3 start.

Caleb Joseph went deep for the Orioles, who extended their major-league best home run total to 16 but still had a two-game win streak stopped.

Orioles starter Ubaldo Jimenez was ousted in the fourth inning with two away by home-plate umpire Jordan Baker after hitting Pablo Sandoval on the shoulder.

"It was my first one. I was shocked," Jimenez said of getting the heave "He's a good hitter and I'm trying to go inside."

The Orioles were 11-8 against Boston last season.