| Player | Team | GP | GS | MP | G | GWG | PK | PKG | A | S | SOT |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Wayne Rooney | Manchester United | 34 | 32 | 2838 | 27 | 9 | 8 | 6 | 5 | 154 | 72 |
| Jonathan Walters | Stoke City | 38 | 38 | 3335 | 7 | 2 | 6 | 4 | 5 | 67 | 19 |
| Scott Sinclair | Swansea City | 38 | 35 | 3122 | 8 | 4 | 5 | 4 | 5 | 88 | 26 |
| Aiyegbeni Yakubu | Blackburn Rovers | 30 | 29 | 2451 | 17 | 1 | 5 | 4 | 2 | 65 | 33 |
| Ben Watson | Wigan Athletic | 21 | 14 | 1262 | 3 | 0 | 4 | 2 | 2 | 17 | 7 |
| Frank Lampard | Chelsea | 30 | 26 | 2250 | 11 | 6 | 4 | 3 | 5 | 57 | 24 |
| Emmanuel Adebayor | Tottenham Hotspur | 33 | 32 | 2840 | 17 | 4 | 4 | 3 | 11 | 96 | 49 |
| Martin Petrov | Bolton Wanderers | 31 | 30 | 2572 | 4 | 0 | 4 | 4 | 7 | 65 | 21 |
| Demba Ba | Newcastle United | 34 | 32 | 2728 | 16 | 3 | 3 | 2 | 2 | 104 | 42 |
| Sergio Agüero | Manchester City | 34 | 31 | 2601 | 23 | 8 | 3 | 3 | 9 | 128 | 52 |
| Leighton Baines | Everton | 33 | 33 | 2970 | 4 | 2 | 3 | 3 | 2 | 25 | 5 |
| Mario Balotelli | Manchester City | 23 | 14 | 1321 | 13 | 4 | 3 | 3 | 1 | 77 | 31 |
| Heidar Helguson | Queens Park Rangers | 16 | 13 | 1156 | 8 | 2 | 3 | 2 | 2 | 45 | 14 |
| Robin Van Persie | Arsenal | 38 | 37 | 3334 | 30 | 11 | 3 | 2 | 11 | 170 | 81 |
| Stephen Hunt | Wolverhampton | 24 | 16 | 1395 | 3 | 0 | 3 | 3 | 1 | 33 | 17 |
| Charlie Adam | Liverpool | 28 | 27 | 2175 | 2 | 1 | 2 | 1 | 6 | 49 | 12 |
| Grant Holt | Norwich City | 36 | 24 | 2246 | 15 | 4 | 2 | 2 | 2 | 74 | 36 |
| Jordi Gómez | Wigan Athletic | 28 | 24 | 1805 | 5 | 2 | 2 | 2 | 1 | 48 | 17 |
| Dimitar Berbatov | Manchester United | 12 | 5 | 513 | 7 | 0 | 2 | 2 | 0 | 17 | 10 |
| Danny Murphy | Fulham | 36 | 33 | 2743 | 3 | 0 | 2 | 2 | 5 | 23 | 11 |
| Darren Bent | Aston Villa | 22 | 21 | 1862 | 9 | 1 | 2 | 2 | 1 | 44 | 26 |
| Dirk Kuyt | Liverpool | 34 | 22 | 2002 | 2 | 0 | 2 | 0 | 1 | 52 | 17 |
| Junior Hoilett | Blackburn Rovers | 34 | 34 | 2955 | 7 | 2 | 1 | 0 | 5 | 55 | 21 |
| Mauro Formica | Blackburn Rovers | 34 | 25 | 2172 | 4 | 1 | 1 | 0 | 1 | 41 | 14 |
| Bobby Zamora | Queens Park Rangers | 29 | 28 | 2376 | 7 | 1 | 1 | 1 | 6 | 50 | 21 |
| Nikica Jelavic | Everton | 13 | 10 | 956 | 9 | 3 | 1 | 1 | 0 | 38 | 18 |
| Didier Drogba | Chelsea | 24 | 16 | 1480 | 5 | 2 | 1 | 1 | 1 | 64 | 18 |
| Shane Long | West Bromwich Albion | 32 | 24 | 2186 | 8 | 1 | 1 | 1 | 1 | 42 | 23 |
| Chris Brunt | West Bromwich Albion | 29 | 25 | 2309 | 2 | 1 | 1 | 0 | 6 | 48 | 11 |
| James Milner | Manchester City | 26 | 17 | 1579 | 3 | 0 | 1 | 1 | 5 | 15 | 8 |
